Corona Virus Q&A

Corona Virus Q&A

Posted by Sade "Bazi" Walker on Aug 23rd 2021

Blood Brain Barrier: Does vaccine cross: Yes, Nanolipids can cross the blood brain barrier. Note: COVID causes systemic inflammation that opens the BBB, it also binds to receptor sites in the brain and crosses; One of the reasons for loss of taste, smell and "air hunger".  NanoLipids will be used in future to deliver drugs to Central Nervous System to increased effectiveness of Neurological disorders.

Are Nanolipids safe? New studies are being done to determine if allergic reactions are possibly due to PEG and other nanolipids. PEG is found in many foods and medicines and some people may be hyper sensitive to it. New studies are being done to determine if allergic reactions are possibly due to PEG and other nanolipids.

Does Ivermectin work? In doses safe for humans, Moderate-certainty evidence finds that large reductions in COVID-19 deaths are possible using ivermectin. Using ivermectin early in the clinical course may reduce numbers progressing to severe disease. The apparent safety and low cost suggest that ivermectin is likely to have a significant impact on the SARS-CoV-2 pandemic globally. Ivermectin at the usual doses (0.2–0.4 mg/kg) is considered extremely safe for use in humans.6,7 In addition to its antiparasitic activity, it has been noted to have antiviral and anti-inflammatory properties, leading to an increasing list of therapeutic indications. Proposed Mechanism of Action and Rationale for Use in Patients With COVID-19 Reports from in vitro studies suggest that ivermectin acts by inhibiting the host importin alpha/beta-1 nuclear transport proteins, which are part of a key intracellular transport process that viruses hijack to enhance infection by suppressing the host’s antiviral response.4,5 In addition, ivermectin docking may interfere with the attachment of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to the human cell membrane.6 Ivermectin is thought to be a host-directed agent, which may be the basis for its broad-spectrum activity in vitro against the viruses that cause dengue, Zika, HIV, and yellow fever.4,7-9 Despite this in vitro activity, no clinical trials have reported a clinical benefit for ivermectin in patients with these viruses. Some studies of ivermectin have also reported potential anti-inflammatory properties, which have been postulated to be beneficial in people with COVID-19.10-12

How do Nanolipids leave the body? Macrophages and kidneys. I'm unable to find study on length of time lipids stay in body, only that researchers tailor the amount of coating to determine length of time and immune response. 

Nanotechnology, what is it? is science, engineering, and technology conducted at the nanoscale, which is about 1 to 100 nanometers. Currently being used for disinfecting agents, testing, biosensors, drug delivery systems.

What are Biosensors? Nanotechnology that can be used to measure internal body chemistry. Future uses include blood glucose monitoring. Current uses are measuring of oxygenation in blood vessels after cardiac stent placement.

Cures for Cancer and HIV: mRNA for cancer and HIV treatment has been underway for some time. Moderna HIV vaccine human phase trials are beginning again soon.

Delta variant - what is it? A mutation in the S-Spike protein. It learns to evade the immune system and has higher rate of transmission.

Delta variant - how is it tracked? CDC requires 10% of COVID samples from some facilities be sent in for testing.

Natural infection or Vaccine – Both have 5 months efficacy ; Having both = increased efficacy. It's unknown how much immune response you have after 5 months. More studies are needed. Viral shedding still occurs with vaccinated individuals despite lesser symptoms.

Do masks work? Masks both surgical and N95 are found to be beyond 90% effective in reducing infections and transmission. Studies were performed with live Coronavirus. 

C19 affects on pregnancy: C19 Crosses the placenta, unknown effects. Fever is associated with defects however. Pregnancy increase during pandemic: Birth rates fall 2% per year in US, 4% previous year and down 8.6% at the end 2020.

Economic impact:

-Jeff Bezos could pay each of Amazons 876,000 employees a $105,000 bonus and still be as wealthy as he was before the pandemic. #ShopLocalBusinesses

-400 Million jobs were lost during the pandemic. More than 50% occurred in low income households and women.

-32 of the world richest companies are expected to make $109 Billion more in than I previous years.

-Corporations did little to support government resources during pandemic. 0.5% of profits were donated.

-Excessive payouts to shareholders (94%) before the crisis left companies, workers and government vulnerable to pandemic shock.

-Profiting from government relief programs despite lack of eligibility

-Lobbying in government to decrease shareholder protection.

-Shifting cost and risks down the supply chain #ShopLocalBusinesses